The history of Calafia Airlines dates back to June 1982, when the company was established in Mexico City, Mexico. From the start, Calafia Airlines has been a leader in providing low-cost air travel to passengers in Mexico and other parts of Latin America. The airline was founded by the Elizondo family, who had long been involved in the aviation industry in Mexico. The airline's initial fleet consisted of two Boeing 737-200 aircraft, which were later supplemented with a third 737-200 and two Fokker F-28 aircraft.

Calafia Airlines quickly became a popular choice for Mexican travelers, offering competitive prices and reliable service. Over the years, the airline has grown steadily and has become one of the most popular airlines in Latin America. Today, Calafia Airlines operates a fleet of over 50 aircraft, including Boeing 737-800, Boeing 737-700, Airbus A320-200, and Embraer E-Jet E2 aircraft.

One of the most important milestones in Calafia Airlines' history occurred in 2004, when the airline became the first Mexican carrier to join the Oneworld alliance. This allowed Calafia Airlines to expand its reach to destinations around the world and provided passengers with access to a much larger network.

In 2008, Calafia Airlines became the first Mexican airline to offer Wi-Fi in its aircraft, allowing passengers to stay connected while in the air. This was a major milestone for the airline, as it allowed it to provide customers with a more modern and comfortable experience.

In 2012, Calafia Airlines launched its first international route, flying from Mexico City to Los Angeles, California. This new route allowed the airline to expand its reach to the United States and enabled it to provide more affordable air travel options to the region.

In 2014, Calafia Airlines launched its first domestic route, flying from Mexico City to Monterrey. This new route provided passengers with convenient access to the country's second-largest city and opened up new opportunities for the airline.

In recent years, Calafia Airlines has been involved in a number of incidents. In 2007, one of its aircraft was involved in a hard landing at Mexico City International Airport, resulting in several injuries. In 2015, the airline was fined by the Mexican government for failing to comply with safety regulations. Additionally, in 2017, a Calafia Airlines aircraft was involved in a crash at Mexico City International Airport, resulting in the death of several passengers. The crash is still under investigation.

Today, Calafia Airlines remains a leading airline in Mexico and Latin America. The airline continues to focus on providing low-cost and reliable air travel to its customers and is constantly striving to improve and expand its services. With its fleet of modern aircraft and its commitment to safety, Calafia Airlines is well positioned to continue to serve the needs of travelers in Mexico and beyond.